Publications
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Publications
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2025
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Dissertation
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Elucidating the Metalation Pathway of the E$_{c}$-1 Metallothionein β$_{E}$-Domain: Insights into Zn$^t{II}$ Binding and Protein Folding and Developing a New Synthetic Pathway to Site-Specifically Label Adenosines in DNA Through a Modular System (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-279233
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Mild High-Yielding Site-Selective C–H Arylation of Arenes (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-277701
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2024
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Journal Article
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“Covalent‐Disassembly”‐Based Approaches For Sensing Applications Chemistry, 30, e202302705. https://doi.org/10.1002/chem.202302705
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Dissertation
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Investigation of the Binding Requirements of the $\textit{moaA}$ Riboswitch (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-263129
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Crystal Engineering in Sb$_{2}$Se$_{3}$ Photocathodes for Solar Hydrogen Production Enhancement (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-261297
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Short Peptides as Selective Chelating Agents for Lead Detoxification (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-259350
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2023
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Journal Article
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An Al-salen complex for the fluorometric detection of pyrophosphate in water via a disassembly approach Journal of Porphyrins and Phthalocyanines, 27, 661–669. https://doi.org/10.1142/S1088424623500578
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2022
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Journal Article
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A CuII-Salicylidene Glycinato Complex for the Selective Fluorometric Detection of Homocysteine over 20 Proteinogenic Amino Acids ChemistryOpen, 11, e202200106. https://doi.org/10.1002/open.202200106
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Functionalisation of vitamin B12 derivatives with a cobalt β-phenyl ligand boosters antimetabolite activity in bacteria RSC Advances, 12, 28553–28559. https://doi.org/10.1039/d2ra05748d
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2021
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Journal Article
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Redox-Neutral Syntheses and Electrochemical Studies of 10-Bromo-Substituted Light-Stable Antivitamin B12 Candidates Helvetica Chimica Acta, 104, e21000. https://doi.org/10.1002/hlca.202100067
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Induced fit activity-based sensing: a mechanistic study of pyrophosphate detection with a “flexible” Fe-salen complex Inorganic Chemistry Frontiers, 8, 4313–4323. https://doi.org/10.1039/d1qi00209k
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Detection of glyphosate with a copper(ii)-pyrocatechol violet based GlyPKit Analytical Methods, 13, 4354–4360. https://doi.org/10.1039/d1ay01168e
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Reversible metal-centered reduction empowers a Ni-Corrin to mimic F430 Chemical Communications, 57, 7260–7263. https://doi.org/10.1039/d1cc02945b
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Dissertation
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Fluorometric and Colorimetric Selective Detection of Biologically and Environmentally Relevant Phosphates (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-215278
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Syntheses and Studies of Vitamin B12 Derivatives Containing Nickel, Cobalt and Zinc – From Cofactor F430-Inspired Chemistry to Potential Antibiotics (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-215283
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2020
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Journal Article
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Metal-Salen-based Probes for the Selective Detection of Phosphates via a Disassembly Approach Chimia, 74, 252–256. https://doi.org/10.2533/chimia.2020.252
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FeIII–salen based Probes for the Selective and Sensitive Detection of E450 in Foodstuff Chemistry, 26, 5717–5723. https://doi.org/10.1002/chem.201905686
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Dissertation
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Nanomaterials for Drug Delivery and Multi-Modal Imaging (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-199265
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2019
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Journal Article
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Quantifying cyanide in water and foodstuff using corrin-based CyanoKit technologies and a smartphone The Analyst, 144, 130–136. https://doi.org/10.1039/c8an01059e
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2018
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Journal Article
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A Nickel(II)-Containing Vitamin B12 Derivative with a Cofactor-F430-type π-System Angewandte Chemie Internationale Edition, 57, 16308–16312. https://doi.org/10.1002/anie.201810983
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Modified vitamin B12 derivatives with a peptide backbone for biomimetic studies and medicinal application Journal of Porphyrins and Phthalocyanines, 22, 535–541. https://doi.org/10.1142/s108842461830001x
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Stabilizing intramolecular cobalt–imidazole coordination with a remote methyl group in the backbone of a cofactor B12–protein model Dalton Transactions, 47, 10443–10446. https://doi.org/10.1039/c8dt01298a
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Determination of the formal redox potentials of the cyanhaemoglobin/cyanmethaemoglobin and the myoglobin/metmyoglobin couples at neutral pH Bioelectrochemistry, 120, 83–86. https://doi.org/10.1016/j.bioelechem.2017.11.012
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2017
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Journal Article
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Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release Chemical Communications, 53, 6840–6843. https://doi.org/10.1039/C7CC03642F
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2016
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Journal Article
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Inorganic cyanide as protecting group in the stereospecific reconstitution of vitamin B12 from an artificial green secocorrinoid Organic Letters, 18, 5292–5295. https://doi.org/10.1021/acs.orglett.6b02611
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A disassembly strategy for imaging endogenous pyrophosphate in mitochondria by using an feiii-salen complex Chembiochem, 17, 1211–1215. https://doi.org/10.1002/cbic.201600195
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Modulating the cobalt redox potential through imidazole hydrogen bonding interactions in a supramolecular biomimetic protein-cofactor model Chemical Science, 7, 3836–3842. https://doi.org/10.1039/C5SC04396D
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2015
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Journal Article
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Detecting biologically relevant phosphates with locked salicylaldehyde probes in water Chemical Communications, 51, 17170–17173. https://doi.org/10.1039/C5CC07413D
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Recent trends in the development of vitamin B12derivatives for medicinal applications Chemical Communications, 51, 14004–14017. https://doi.org/10.1039/C5CC04843E
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Reply to the ‘Comment on “Rapid visual detection of blood cyanide”’ by A. F. Kadjo, P. K. Dasgupta and G. R. Boss, Analytical Methods, 2015,7, DOI: 10.1039/C4AY00190G Analytical Methods, 7, 5712–5713. https://doi.org/10.1039/C4AY02352H
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Antivitamins for Medicinal Applications Chembiochem, 16, 1264–1278. https://doi.org/10.1002/cbic.201500072
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Corrin-based chemosensors for the ASSURED detection of endogenous cyanide Organic & Biomolecular Chemistry, 13, 14–17. https://doi.org/10.1039/C4OB01889C
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Anion sensing with cobalt corrinoid grafted quartz crystal microbalances Sensors and Actuators B: Chemical, 207, 297–302. https://doi.org/10.1016/j.snb.2014.10.073
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Cyanide detection in gastric juice with corrin-based chemosensors Analytical Methods, 7, 9707–9712. https://doi.org/10.1039/C5AY02600H
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Scientific Publication in Electronic Form
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Vitamin B12-basierte Chemosensoren: Effizienter Nachweis von Zyaniden http://www.git-labor.de/forschung/lebensmittel/vitamin-b12-basierte-chemosensoren-effizienter-nachweis-von-zyaniden
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2014
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Journal Article
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Controlling binding dynamics of corrin-based chemosensors for cyanide Inorganic Chemistry, 53, 2516–2520. https://doi.org/10.1021/ic4026427
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Straightforward rapid spectrophotometric quantification of total cyanogenic glycosides in fresh and processed cassava products Food Chemistry, 158, 20–27. https://doi.org/10.1016/j.foodchem.2014.02.066
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2013
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Journal Article
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Synthesis of a B ring opened 7,8-seco-Vitamin B12Derivative with Grob fragmentation Organic Letters, 15, 4630–4633. https://doi.org/10.1021/ol401572j
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Peptide B12: emerging trends at the interface of inorganic chemistry, chemical biology and medicine Dalton Transactions, 854–862. https://doi.org/10.1039/C2DT32005C
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Habilitation
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Studies on modified vitamin B12 derivatives – from fundamentals to applications (Habilitation, University of Zurich)
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2012
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Journal Article
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Chemistry and Bioactivity of an Artificial Adenosylpeptide B12 Cofactor Chembiochem, 2052–2055. https://doi.org/10.1002/cbic.201200429
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Rapid visual detection of blood cyanide Journal of Analytical Methods in Chemistry, 4, 2632–2634. https://doi.org/10.1039/C2AY25595B
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Cobinamide chemistries for photometric cyanide determination. A merging zone liquid core waveguide cyanide analyzer using cyanoaquacobinamide Analytica Chimica Acta, 736, 78–84. https://doi.org/10.1016/j.aca.2012.05.028
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Complex samples cyanide detection with immobilized corrinoids ACS Applied Materials & Interfaces, 4, 725–729. https://doi.org/10.1021/am201357u
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Experimental study of hydrogen bonding potentially stabilizing the 5’-Deoxyadenosyl radical from coenzyme B12. Chemistry, 18, 16114–16122. https://doi.org/10.1002/chem.201201840
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Book Section
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Vitamin B12 derivatives for spectroanalytical and medicinal applications In K. M. Kadish, K. M. Smith, & R. Guilard (Eds.), Handbook of Porphyrin Science (No. 25; pp. 83–130). World Scientific. https://doi.org/10.1142/9789814397605_0018
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2011
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Journal Article
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One-step synthesis of alpha/beta cyano-aqua cobinamides from vitamin B12 with Zn(II) or Cu(II) salts in methanol Journal Of Porphyrins And Phthalocyanines, 15, 555–559. https://doi.org/10.1142/S1088424611003446
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Identification of diastereomeric cyano-aqua cobinamides with a backbone-modified vitamin B12 derivative and with (1)H NMR spectroscopy European Journal of Inorganic Chemistry, 2011, 53–57. https://doi.org/10.1002/ejic.201001146
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Immobilised vitamin B12 as a biomimetic model for base-off/histidine-on coordination Chemical Communications, 47, 11249–11251. https://doi.org/10.1039/c1cc15093f
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