Navigation auf uzh.ch
"Seeing is Believing": Visualization of biomolecules offers a fascinating and powerful way to observe complex processes such as binding events and folding pathways in real-time. Our research is dedicated to unraveling the dynamic behavior of catalytically active RNAs and understanding how their structures are intricately linked to their functions. To achieve this, we employ a range of innovative RNA labeling strategies that allow us to explore these processes at the single-molecule level. Advanced techniques like Förster Resonance Energy Transfer (smFRET) and Fluorescence Correlation Spectroscopy (FCS) provide us with a window into the molecular choreography of these vital biomolecules, offering unprecedented insights into their roles in biological systems.
Research Experiences