Navigation auf uzh.ch

Suche

Department of Chemistry Sigel Lab

Abdul Rahman Sadiq

Abdul Rahman Sadiq

Phone
+41 44 63 54648
Room number
Y19-K-46

Research projcet

Group II introns are large self-splicing ribozymes that have been extensively studied, providing critical insights into RNA splicing mechanisms and potential therapeutic applications. While crystal structures provide valuable static snapshots of their architecture, they do not capture the dynamic structural rearrangements that occur during catalysis. To address this, we use single-molecule Förster resonance energy transfer (smFRET) to track RNA dynamics in real time, providing a deeper understanding of their structural transitions and interactions. Our research demonstrates the power of smFRET in the study of RNA function.

Behind the Lab Coat: My Inspirations and Passions

Year you joined the Sigel Lab: 2023
Scientist hero: Manu Prakash
Class or teacher that inspired me: High School English Language teacher.
Outside of the lab, I enjoy watching and playing football.

Education

Since 2023 PhD in the group of Prof. Roland K. O. Sigel
2017 – 2022 Integrated BS-MS (Bachelor of Science - Master of Science), with Biology Major, Indian Institute of Science Education and Research, Tirupati
2014 – 2016 Higher Secondary Education
Gov. Higher Secondary School Venjaramoodu, Kerala, India

 

Work Experience

May 2021 – April 2022

MS Thesis project, Single Molecule Biophysics Lab, IISER Tirupati

Supervisor: Dr Nibedita Pal, Assistant Professor, Department of Biology, IISER Tirupati on the project titled
"Investigating the interaction of BRCA1 protein with human telomeric
G-quadruplex DNA"
January 2021 – April 2021

Semester Project, Single Molecule Biophysics Lab, IISER Tirupati

Supervisor: Dr. Nibedita Pal, Assistant Professor, Department of Biology, IISER Tirupati on the project titled
"Assembling and characterization of state-of-the-art Fluorescence Correlation Spectrometer (FCS)".
May 2019 – June 2019

Summer Internship, CSIR - NIIST, Thiruvananthapuram, India

Supervisor: Dr. Priya S, Dept. of Agro Processing and Technology, CSIR – NIIST on Basic Animal Cell Culture Techniques.