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Soumyadip Jana

Soumyadip Jana

Phone
+41 44 63 54640
Room number
Y19-K-88

Research project

I am amazed by biomolecular structures and their intricate dynamics for biological function. HDV-like ribozymes are found in all life forms, but their structure and function are largely unexplored. These ribozymes fold into an intricate 'nested double pseudoknot' and are capable of self-cleavage through a transesterification reaction. Minimal HDV-like ribozymes are shorter variants that lack a base-paired domain but retain HDV-like folding and catalytic activity. I am studying one of the minimal HDV-like ribozymes using NMR spectroscopy to gain insight into its 3D structure and self-cleavage pathway, with the aim of applying this knowledge to the whole class of ribozymes.

Behind the Lab Coat: My Inspirations and Passions

Year I joined the Sigel lab: 2022
My favourite molecule: Porphyrins
Scientist Hero: Venki Ramakrishnan.
If I could go anywhere, I would go to the top of Mount Everest.
Outside the lab, I enjoy going for sports such as tennis, badminton, or football and I regularly go hiking in the Swiss Alps on the weekends.

Education

12/2022 – today

PhD student in the group of Prof. Roland K. O. Sigel
Department of Chemistry, University of Zurich

08/2021 – 04/2022

Master thesis in biophysical chemistry in the group of Dr. Bharathwaj Sathyamoorthy
Role of G-quadruplexes as catalyst in enantioselective cyclopropanation.
Department of Chemistry, Indian Institute of Science Education and Research, Bhopal

07/2017 – 07/2022

Integrated BS-MS program in Chemistry
Department of Chemistry, Indian Institute of Science Education and Research (IISER), Bhopal

03/2015 - 03/2017

Higher Secondary studies specialized in science
West Bengal Council of Higher Secondary Education

Professional Experience

11/2021 – 12/2021

Stochasticity in gene expression: Reproduce plots of from 2-stage and 3-stage gene expression models from a research paper on Analytical distributions for stochastic gene expression using python at IISER Bhopal.

05/2021 – 06/2021

Internship on Sequential chemical shift assignments of duplex DNAs at IISER Bhopal.

05/2019 – 07/2019

Summer Internship on Synthesis and study of 1,8-napthalimide derivatives for AIE properties at IISER Bhopal.

05/2018 – 07/2018

Summer Internship on Synthesis of porphyrin derivatives and monitoring its properties with UV spectroscopy at IISER Bhopal.