Equipment

Thermo DFS

High-resolution mass analyzer (GC-)MS equipped with electron- and chemical-ionization (EI and CI), direct chemical ionization (DCI), gas chromatograph (GC), and autosampler incl. headspace sampling and automatic derivatization. Suited for the analysis of small and volatile molecules with rather low polarity that can be evaporated without decomposition.

Instrument description file: 

InstrDescr_(GC-)HR-MS_DFS (PDF, 74 KB)

Bruker timsTOF Pro

High-resolution ion mobility QTOF UHPLC-MS(/MS) fitted optionally with electrospray ionization, atmospheric pressure chemical ionization, and atmospheric photoionization sources (ESI, APCI or APPI). This system with a resolution up to 70’000, a mass accuracy ≤ 2 ppm and an extended mass range (m/z 50-20'000) allows MS/MS experiments, calculation of the collision cross section of ions (CSS), and is on-line coupled to a Vanquish UHPLC system (up to 1500 bar).
Suited for structure elucidation and quantification of labile compounds in complex samples (e.g. polar compounds, metal complexes, biopolymers) biological extracts). Separation of ions with the same mass such as structural isomers is possible.

Instrument description file:

InstrDescr_LC-HR-IM-MS_timsTOFPro (PDF, 115 KB)

Thermo QExactive

High-resolution Orbitrap HPLC-MS(/MS) instrument fitted with an electrospray- or atmospheric pressure ion source (ESI or APCI). This system has a resolution up to 140’000, a mass accuracy ≤ 2 ppm, an extended mass range (m/z 50-6000) and is on-line coupled to an Ultimate 3000 UHPLC system (up to 1000 bar).
Suited for structure elucidation and quantification of labile compounds in complex samples (e.g. polar compounds, metal complexes, and biopolymers) and complex biological extracts.

Instrument description file:

Bruker AutoflexSpeed

Maldi-TOF instrument equipped with Smartbeam laser and stainless steel targets. A thin-layer chromatography plate adapter allows Maldi imaging of TLC plates. Suited for the analysis of polyaromatic hydrocarbones, dendrimers, peptides, proteins, polymer, and metal complexes of higher MR. Mass accuracy ≤ 5 ppm.

Instrument description file:

Agilent 8800 ICP-MS

Inductively coupled plasma triple quadrupole mass spectrometer equipped with a standard micro-flow sprayer or an apex-IR nebulizer.
Suited quantification of elements in ultra-trace level in organic, inorganic, and biological samples.

Instrument description file: 

InstrDescr_ICP-MS_Agilent8800 (PDF, 58 KB)