E. Riaplov, Q.
Li, S. Seeger: Ultrasensitive staining-free protein detection after PAA
gel electrophoresis using deep UV fluorescence detection , Protein
& Peptide Letters 14, 712-715 (2007)
Q.
Li, S. Seeger: Label free detection of protein interactions using deep
UV fluorescence lifetime microscopy, Analytical Biochemistry 367, 104-110 (2007)
J. Zimmermann, F. A. Reifler, U. Schrade, G. J. R. Artus, S. Seeger:
Long term environmental durability of a superhydrophobic silicone
nanofilament coating, Colloids and Surfaces A: Physicochemical and
Engineering Aspects 302, 234-240 (2007)
M.
Rabe, D. Verdes, M. Rankl, G. J. R. Artus, S. Seeger: A Comprehensive
Study of Concepts and Phenomena of the Non-specific Adsorption of b-Lactoglobulin, ChemPhysChem 8, 862-872 (2007)
D.
Verdes, T. Ruckstuhl, S. Seeger: Parallel two channel near and far
field fluorescence microscopy, Journal of Biomedical Optics 12 (3), 034012 (2007)
J. Zimmermann, G. R. J. Artus, S. Seeger: Long term studies on the
chemical stability of a superhydrophobic silicone nanofilament coating,
Applied Surface Science 253, 5972-5979 (2007)
2006
S. Seeger: Label
Free Detection of Single Native Proteins: Ultimate Sensitivity and
Convenience, Chimia, Highlights of Analytical Chemistry in Switzerland,
60 (12/06) 854 (2006)
Q. Li, S. Seeger: Label free detection of single protein molecules
unsing deep UV fluorescence lifetime microscopy, Analytical Chemistry 78, 2732-2737 (2006)
A.
Krieg, T. Ruckstuhl, S. Seeger: Towards single-molecule DNA sequencing:
Assays with low nonspecific adsoption, Analytical Biochemistry 349, 181-185 (2006)
E.
Stoinski-Bungs, S. Seeger, W. Kemmner, P. Scheinert, G. Krupp: Laser
microdissection of a colon cancer specimen with subsequent RNA
isolation, mRNA amplification and microarray hybridization, Nature
Methods 10-11, Suppl. S. (2006)
S.
Laib, A. Krieg, M. Rankl, S. Seeger: Supercritical angle fluorescence
biosensor for the detection of molecular interactions on
cellulose-modified glass surfaces, Surface Science, Applied Surface
Scienc 252, 7788-7793 (2006)
M. Rankl, T. Ruckstuhl, G. R. J. Artus, A. Walser,
S. Seeger: Conformational reorientation of Immunglobulin G during
non-specific interaction with surfaces, ChemPhysChem 7, 837-846, (2006)
S.
Jung, B. Angerer, S. Niehren, J. Winkle, F. Löscher, S. Seeger: Biotin
functionalized cellulose-based monolayer as sensitive interface for
detection of single molecules, ChembioChem, ChemBioChem 7 (6), 900-903, (2006)
G. R. J. Artus, S. Jung, J. Zimmermann, H.-P. Gautschi, K. Marquardt,
S. Seeger: Silicone Nanofilaments and their Application as
Superhydrophobic Coating, Advanced Materials, 18, 2758-2762 (2006)
S. Seeger: Von der Innovationsflut zum wirtschaftlichen Erfolg:
Selektion, Kooperation, Organisation. Innovationsmanagement in jungen,
kleinen und mittleren Unternehmen, Herausgeberband, Innovationen
erfolgreich organisieren, Lehren und Erfahrungen von
Innovationschampions (Konzeption Michael Nippa, Kai Engel),111-129
(2006)
2005
T.
Ruckstuhl, A. Walser, D. Verdes, S. Seeger: Confocal Reader for Biochip
Screening and Fluorescence Microscopy, Biosensors and Bioelectronics 20, 1872-1877 (2005)
S.V. Roth, G.R.J. Artus, M. Rankl, S. Seeger, M.
Burghammer, C. Riekel, P. Müller-Buschbaum: Lateral structural
variations in thin cellulose layers investigated by microbeam grazing
incidence small-angle X-ray scattering, Physica B, 357, 190-192 (2005)
H. Grubmüller, S. Seeger, H. Tschesche: Aufbau, Funktion und Diagnostik
biogener Moleküle, Bergmann Schaefer, Lehrbuch der Experimentalphysik Band 5, Gase, Nanosysteme, Flüssigkeiten, (Herausgeber Karl Kleinermanns), 977-1067 (2005)
2004
S. Seeger: Ultrasensitive Fluorescence Detection at Surfaces:
Instrument Development, Surface Chemistry and Applications in Life
Science and Medicine, EPS Book Series: Comprehensive Series in Photoscience (D.-P. Häder, G. Jori, Series editors), 4, Lasers and Current Optical Techniques in Biology , 609-636 (2004)
A.
Krieg, S. Laib, T. Ruckstuhl, S. Seeger: Fast detection of Single
Nucleotide Polymorphisms (SNPs) by Primer Elongation with Monitoring of
Supercritical-Angle Fluorescence, ChemBioChem, 12, 1680-1685 (2004)
T. Ruckstuhl, S. Seeger: Attoliter detection volumes by confocal total-internal-reflection
fluorescence microscopy, Optic Letters 29, 569-571 (2004)
Q. Li, T. Ruckstuhl, S. Seeger: Deep-UV Laser-based Fluorescence
Lifetime Imaging Microscopy of Single Molecules, J. Physical Chemistry
B 108, 8324-8329 (2004)
S. Laib, S. Seeger: FRET studies of the interaction of dimeric cyanine
dyes with DNA, J. Fluorescence 14 (2) 187-191 (2004)
A. Krieg, T. Ruckstuhl, S. Laib, S. Seeger: Real-time detection of
polymerase activity using supercritical angle fluorescence, J. Fluorescence 14 (1) 75-78 (2004)
2003
G. Artus, S. Jung, S. Seeger: Superhydrophobic Coating, Europäisches
Patentamt, EP 03405455.1 (2003)
S. Laib, M. Rankl, T. Ruckstuhl, S. Seeger: Sizing of single fluorescently
stained DNA-fragments by scanning microscopy, Nucleic Acids Research
31 (22) e138 (2003)
T. Ruckstuhl, M. Rankl, S. Seeger: Confocal TIRF microscopy of single
molecules, Proc. SPIE 4962, 126-134 (2003), Manipulation and Analysis
of Biomolecules, Cells, and Tissues; D. V. Nicolau, J. Enderlein, R.
C. Leif, D. L. Farkas; Eds.
T. Ruckstuhl, S. Seeger: Confocal total-internal-reflection fluorescence
microscopy with a high-aperture parabolic mirror lens, Appl. Opt. 42 (16) 3277-3283 (2003)
A. Krieg, S. Laib, T. Ruckstuhl, S. Seeger: Real-time Detection of
Nucleotide Incorporation During Complementary DNA Strand Synthesis,
Chembiochem. 4, 589-592 (2003)
M. Rankl, S. Laib, S. Seeger: Surface tension properties of surface-coatings
for application in biodiagnostics determined by contact angle measurements,
Colloids and Surfaces B: Biointerfaces 30 (3) 177-186 (2003)
T. Ruckstuhl, M. Rankl, S. Seeger: Highly sensitive biosensing using
a Supercritical Angle Fluorescence (SAF) instrument, Biosensors&Bioelectronics
18 (9) 1193-1199 (2003)
R. C. Krieg, H. Messmann, K. Schlottmann, E. Endlicher, S. Seeger, J.
Scholmerich, R. Knuechel: Intracellular localization is a cofactor for
the phototoxicity of protoporphyrin IX in the gastrointestinal tract:
In vitro study, Photochemistry and Photobiology, 78 (4) 393-399 (2003)
2002
R. C. Krieg, H. Messmann, J. Rauch, S. Seeger, R. Knuechel: Metabolic
Characterization of Tumor Cell-specific Protoporphyrin IX Accumulation
after Exposure to 5-Aminolevulinic Acid in Human Colonic Cells, Photochemistry
and Photobiology, 76 (5) 25-32 (2002)
2001
S. Seeger: Biosensorik: Präziser...kleiner...Einzelmoleküle,
LaborPraxis, LabFuture Sonderausgabe 2002, 80-82 (2001)
2000
T. Ruckstuhl, J. Enderlein, S. Jung, S. Seeger: Forbidden Light Detection
from Single Molecules, Anal. Chem. 72, 2117 (2000)
1999
S. Seeger: HTS with Single Molecule Sensitivity, CHIMICA OGGI / chemistry
today, July/August (1999)
J. Enderlein, T. Ruckstuhl, S. Seeger: Highly efficient optical detection
of surface-generated fluorescence, Proc. SPIE 3603, 4-13 (1999)
M. Zahn, D. Kurzbuch, F. Pampaloni, S. Seeger: Optical Tweezers as
a Tool for studying Molecular Interactions at Surfaces, Proc. SPIE 3604,
90-99 (1999)
M. Zahn, J. Renken, S. Seeger: Fluorimetric Multiparameter Cell Assay
at the Single Cell Level fabricated by Optical Tweezers, FEBS Letters
443, 337-340 (1999)
J. Enderlein, T. Ruckstuhl, S. Seeger: Highly Efficient Optical Detection
of Surface-Generated Fluorescence. Appl. Opt. 38 (4) 724-32 (1999)
J. Enderlein, T. Ruckstuhl, F. Löscher, M. Böhmer, S. Seeger:
Comparison between a conventional epiluorescence microscope and a new
highly efficent evanescent wave detector in single molecule spectroscopic
applications, Proc. SPIE 3603, 94-101 (1999)
1998
F. Löscher, S. Böhme, J. Martin, S. Seeger: The Counting
of Single Protein Molecules at Interfaces and the Application in Early-Stage-Diagnosis,
Analytical Chemistry 70, 3202-3205 (1998)
S. Seeger, J. Enderlein, F. Löscher: Verfahren und Vorrichtung
zur Konzentrations-Bestimmung, Bestimmung von Adsorptions- und Bindungskinetiken
und Gleichgewichts- und Bindungskonstanten von Molekülen durch
Lumineszenzmessungen, Deutsches Patentamt DE 198 22 542.4 (1998)
T. Ruckstuhl, S. Seeger: Optische Anordnung zum Erfassen von Licht.
Deutsches Patentamt 198 10 615.7 (1998)
S. Seeger: Verfahren zur DNS- oder RNS-Sequenzierung, Deutsches Patentamt
DE 198 44 931.3 (1998)
M. Zahn, S. Seeger: Optical Tweezers in Pharmacology. Cell. Mol.
Biol. 44 (5) 747-762 (1998)
S. Seeger: Einzelmolekülfluoreszenz: Molekulare Hochleistungsdiagnostik
und Wirkstoffscreening, Bioforum 4, 179-185 (1998)
F. Löscher, T. Ruckstuhl, S. Seeger: Ultrathin Cellulose-based
Layers for Detection of Single Antigen Molecules. Advanced Materials
10 (13) 1005-1009 (1998)
F. Löscher, T. Ruckstuhl, T. Jaworek, G. Wegner, S. Seeger:
Immobilization of Biomolecules on Langmuir-Blodgett-Films of Regenerative
Cellulose Derivatives, Langmuir 14, 2786-2789 (1998)
M. Zahn, B. Götz, A. Faissner, S. Seeger: Optical tweezers as
a tool for the functional analysis of neuronal cell membrane receptors.
Proc. SPIE 3199, 156-167 (1998)
S. Seeger: Parallele Festphasensynthese, Deutsches Patentamt DE 198
44 988.7 (1998)
1997
M. Sauer, J. Arden-Jacob, K.H. Drexhage, N.J. Marx, A.E. Karger,
U. Lieberwirth, R. Müller, M. Neumann, S. Nord, A. Paulus, A. Schulz,
S. Seeger, C. Zander, J. Wolfrum: On-line Diode Laser Based Detection
of Labelled Oligonucleotides in Capillary Gel Electrophoresis. Biomed.
Chromatogr. 11 (2) 81-82 (1997)
U. Lieberwirth, M. Sauer, J. Arden-Jacob, K.H. Drexhage, S. Nord,
S. Seeger, A. Schulz, J. Wolfrum: Development of new Multiplex dyes:
Intramolecular fluorescence quenching of rhodamines dyes. J. Fluorescence
7 (1, Suppl.) 59S-61S (1997)
S. Nord, M. Sauer, J. Arden-Jacob, K.H. Drexhage, U. Lieberwirth,
S. Seeger, J. Wolfrum: Ground and excited state reactions of new red
fluorescent dyes and the DNA base guanosine. J. Fluorescence. 7 (1,
Suppl.), 79S-81S (1997)
F. Löscher, S. Seeger: Verfahren zur Beschichtung von Oberflächen
mit definierten Molekülschichten, Deutsches Patentamt 19736736.4
(1997)
F. Löscher, S. Böhme, J. Martin, S. Seeger: Detection of
Single Protein Molecules at Interfaces after Antibody-Antigen-Binding.
Proc. SPIE 3199, 168-177 (1997)
B. Ullrich, S. Seeger, J. Wolfrum: Verwendung von lumineszierenden
Ruthenium(II)-Komplexen zur Markierung von Antikörpern , J. of
Organometallic Chemistry 541, 401-406 (1997)
1996
M. Martin, S. Kaul, U. Drechsler, M. Geyer, R. Kurek, M. Hanack,
S. Seeger, D. Wallwiener, J. Wolfrum. In vitro phototoxicity of a new
phthalocyanine immunoconjugate for use in photodynamic therapy. Proc.
SPIE-Int. Soc. Opt. Eng. 2924 (Photochemotherapy: Photodynamic Therapy
and Other Modalities II), 153-159 (1996)
D. Bock, S. Kaul, F. Löscher, T. Ruckstuhl, V. Schulz, J. Ueberfeld,
S. Seeger: Detection of the Tumormarker Mucine with Diode Laser-based
Evanescent Wave Sensor. Proc. SPIE 2928, 200 (1996)
F. Löscher, A. Hartmann, J. Ueberfeld, T. Ruckstuhl, D. Bock,
T. Jaworek, G. Wegner, S. Seeger: Cellulose-protein Films for highly
specific evanescent wave immunosensors. Proc. SPIE 2928, 209 (1996)
M. Furch, J. Ueberfeld, A. Hartmann, D. Bock, S. Seeger: Ultrathin
Oligonucleotide Layers for Fluorescence Based DNA sensors. Proc. SPIE
2928, 220 (1996)
S. Seeger: Verfahren und Vorrichtung zur Präparierung von Molekülen
und Partikeln, Deutsches Patentamt (1996)
B. Götz, J. Renken, S. Seeger, A. Faissner: Identification of
Tenascin (TN-C) Domains Involved in Axonal Guidance, Europ. J. Cell
Biol., Supplement 42 (Vol. 69) 114 (1996)
J. Renken, B. Götz, A. Faissner, S. Seeger: Studying Cell Adhesion
with Optical Tweezers, Europ. J. Cell Biol., Supplement 42 (Vol. 69)
16 (1996)
J. Renken, N. Leclerc, S. Seeger: Laser Microtechniques for Cellular
Drug Screening in Pharmaceutical Applications, Europ. J. Cell Biol.,
Supplement 42 (Vol. 69) 15 (1996)
M. Köllner, A. Fischer, J. Arden-Jacob, K.H. Drexhage, R. Müller,
S. Seeger, J. Wolfrum: Fluorescence Pattern Recognition for Ultrasensitive
Molecule Identification: Comparison of Experimental Data and Theoretical
Approximations, Chem. Phys. Lett. 250, 355-360 (1996)
D. Bock, A. Hartmann, S. Kaul, M.Martin, V. Schulz, J. Wolfrum, S.
Seeger: Approaches from a single to a multi parameter evanescent wave
sensor. Proc. SPIE 2629, 96-107 (1996)
Loebau, L., Rumphorst, A., Galla, K., Seeger, S., Wolfrum, K.: Adsorption
of Alkyl-trichlorosilanes on Glass and Silicon Studied by Sum-Frequency-Spectroscopy
and XPS. Thin Solid Films 289 (1-2) 272-281 (1996)
1995
S. Andersson-Engels, M. Corti, N. Kroó, I. Kertész,
T.A. King, R. Pratesi, S. Seeger, H.P. Weber (eds.): Proceedings of
Biomedical Optoelectronics in Clinical Chemsitry and Biotechnology,
SPIE Proc. 2629 (1995)
A. Rumphorst, S. Seeger, H. Duschner: Fluorescence Spectroscopy for
Determination of pH on Tooth Surfaces, J. Dent. Res. 74, 567 (1995)
A. Hartmann, D. Bock, T. Jaworek, S. Kaul, M. Schulze, H. Tebbe,
G. Wegner, S. Seeger: Cellulose-antibody films for highly specific evanescent
wave immunosensors. Proc. SPIE 2629, 108-118 (1995)
B. Ullrich, S. Seeger, J. Wolfrum: Using ruthenium charge transfer
complexes as dyes in the multiplex concept. Proc. SPIE 2629, 88-95 (1995)
A. Rumphorst, S. Seeger, H. Duschner: Immobilised fluorescent dyes
for sensitive pH-measurements on enamel surfaces with fiber optics.
Proc. SPIE, 2629, 119-128 (1995)
J. Renken, S. Seeger: Cell Patterns for Biosensors manufactured with
Laser Tweezers. Proc. SPIE Vol. 2629, 79-86 (1995)
Niehren, S., Kinzelbach, W., Seeger, S., Wolfrum, J.: An All-Solid-State
Flow Cytometer for Counting Fluorescent Microspheres. Analytical Chemistry,
67, 2666-2671 (1995)
Sauer, M., Han, K.T., Müller, R., Nord, S., Seeger, S., Wolfrum,
J., Arden-Jacob, J., Deltau, G., Marx, N.J., Zander, C., Drexhage, K.H.:
New Fluorescent Dyes in the Red Region for Biodiagnostics, J. Fluorescence 5 (3) 247-261 (1995)
A. Hartmann, D. Bock, S. Seeger: One-step Immobilization of Immunoglobulin
G and Potential of the Method for Application in Immunosensors. Sensors
and Actuators 28 (2) 143-149 (1995)
D. Bock, K. Galla, M. Martin, J. Wolfrum, and S. Seeger: Use of Diode
Lasers in an Evanescenct Wave Immunosensors for Stationary and Time-resolved
Detection of Antigens. Sensors and Actuators B 29 (1-3) 293-299 (1995)
1994
Hartmann, A., Bock, D, Martin, M., Seeger, S.: Ultrathin Antibody
Networks For Evanescent Detection of Antigens. Proc. SPIE 2331, 50-62
(1994)
S. Seeger, V. Sick, H.R. Volpp, J. Wolfrum: Laser Applications in
Chemistry and Biology: Stimulation, Observation and Manipulation. Israel.
J. Chem. 34, 5-18 (1994)
K. Galla, J. Arden-Jacob, G. Deltau, K.H. Drexhage, M. Martin, M.
Sauer, J. Wolfrum, and S. Seeger: Simultaneous Antigen Detection Using
Multiplex Dyes. J. Fluorescence 4 (1), 111-115 (1994)
A. Rumphorst, H. Duschner, S. Seeger: Optical Determination of pH
on Surfaces Using Immobilized Fluorescent Dyes. J. Fluorescence 4 (1),
45-48 (1994)
A. Hartmann, S. Seeger: Direct Immobilization of Antibodies on Phthalocyaninato-Polysiloxane
Photopolymers. Thin Solid Films, 245, 206-210 (1994)
R. Müller, G. Bachteler, K. T. Han, M. Sauer, S. Seeger, J.
Wolfrum, J. Arden-Jacob, N. J. Marx, K. H. Drexhage: Ultrasensitive
detection of Biomolecules with Multiplex Dyes and Diode Lasers in Capillary
Gel Electrophoresis. in Würzburger Kolloquium, Kapillarelektrophorese,
Chromatographie, Bertsch Verlag, 87-95 (1994)
M. Sauer, K.T. Han, V. Ebert, R. Müller, A. Schulz, S. Seeger,
J. Wolfrum, J. Arden-Jacob, G. Deltau, N.J. Marx, K.H. Drexhage: Design
of Multiplex Dyes for the Detection of Different Biomolecules. Proc.
SPIE 2137, 762-773 (1994)
S. Seeger, J. Arden-Jacob, N. Marx, K.-H. Drexhage, K. Galla, M.
Martin, K.-T. Han, M. Köllner, R. Müller, M. Sauer, J. Wolfrum:
Biodiagnostics with Multiplex Dyes. Proc. SPIE 2136, 75-86 (1994)
G. Bachteler , K.-H. Drexhage, J. Arden-Jacob, K.-T. Han , M. Köllner,
R. Müller, M. Sauer, S. Seeger, J. Wolfrum: Sensitive Fluorescence
detection in Capillary Electrophoresis using Laser Diodes and Multiplex
Dyes. J. Lum. 62, 101-108 (1994)
G. Bachteler , K.-H. Drexhage, J. Arden-Jacob, K.-T. Han , M. Köllner,
R. Müller, M. Sauer, S. Seeger, J. Wolfrum: Sensitive Fluorescence
detection using Laser Diodes and Multiplex Dyes. J. Lum. 60 & 61,
511-514 (1994)
G. Leitz, G. Weber, S. Seeger, K.O. Greulich: The Laser Microbeam
Trap as an Optical Tool for Living Cells. Physiol. Chem. Phys. and Med.
NMR 26, 69-88 (1994)
M. Sauer, K.T. Han, R. Müller, A. Schulz, R. Tadday, S. Seeger,
J. Wolfrum, J. Arden-Jacob, G. Deltau, N.J. Marx, K.H. Drexhage: New
Fluorescenct Labels for Time-Resolved Detection of Biomolecules. J.
Fluorescence 3 (3) 131 (1994)
1993
K.T. Han, M. Sauer, A. Schulz, S. Seeger, J. Wolfrum: Time-resolved
Studies of Labeled Nucleotides. Ber. Bunsenges. Phys. Chem. 97, 1728
(1993)
M. Sauer, A. Schulz, S. Seeger, J. Wolfrum, J. Arden-Jacob, G. Deltau,
K.H. Drexhage: Design of Multiplex Dyes. Ber. Bunsenges. Phys. Chem.
97, 1736 (1993)
S. Seeger, G. Bachteler, K.H. Drexhage, G. Deltau, J. Arden-Jacob,
K. Galla, K.T. Han, R. Müller, M. Köllner, A. Rumphorst, M.
Sauer, A. Schulz, J. Wolfrum: Biodiagnostics and Polymeridentification
with Multiplex Dyes. Ber. Bunsenges. Phys. Chem. 97, 1542 (1993)
E. H. K. Stelzer, N. Leclerc, S. Seeger: Verfahren und Vorrichtung
zur Lumineszenzspektroskopie und Materialmikrobearbeitung von fixierten
und bewegten Molekülen, Partikeln und Objekten. Deutsches Patentamt,
P 4326181.7 (1993)
Hartmann, A., Seeger, S.: Verfahren zur Beschichtung von Oberflächen
mit Biomolekülen und anderen Rezeptormolekülen. Deutsches
Patentamt, P 4332003 (1993)
Seeger, S., Bock, D., Galla, K., Köllner, M., Wolfrum, J.: Verfahren
zum optischen qualitativen und quantitativen Nachweis von Molekülen
und Mikroorganismen. Deutsches Patentamt, P 43 07 042.6 (1993)
1992
Seeger, S., Leclerc, N., Monajembashi, S.: Laser und Lasereinkoppelungsoptik
zur berührungslosen und zerstörungsfreien Manipulation von
Partikeln mit Lichtdruckgradientenkräften. Deutsches Patentamt,
G 92 15 572.3 (1992)
Han, K.-T., Köllner, M., Sauer, M., Seeger, S., Wolfrum, J.,
Schmitt, C., Schulz, A: Verfahren zur optischen Sortierung von Kunststoffen
mittels zeitaufgelöster Laserspektroskopie. Deutsches Patentamt,
P 42 31 477.1 (1992)
Sauer, M., Drexhage, K.H., Han, K.T., Köllner, M., Schulz, A.,
Seeger, S., Seidel, C., Wolfrum, J.: Verfahren zur optischen qualitativen
und quantitativen Erfassung von Biomolekülen, toxischen Substanzen,
Polymeren und pharmazeutischen Wirkstoffen mittels Laserspektroskopie.
Deutsches Patentamt P 42 10 970.1 (1992)
Seeger, S., Bierbaum, K., Dahint, R., Feng C. L., Mantar, M., Grunze,
M.: Preparation and characterization of antibody films on lithium-niobate
crystals. in: Synthetic Microstructures in Biological Research,
J. Schnur, M. Peckerar (eds.). Plenum Publishing Corporation, 53-66
(1992)
1991
Seeger, S., Monajembashi, S., Hutter, K.-J., Futterman, G., Wolfrum,
J., Greulich, K.O.: Application of an Optical Tweezers in Immunology
and Molecular Genetics. Cytometry 12, 497-504, (1991)