CHE 322: Biosynthesis of Natural Products

Vorlesungsunterlagen

Enzyme Chemistry part 1 (PDF, 4 MB)
	Movies: Gycosidase in complex with Substrate, Intermediate and Product
	Movie: Covalent glycosyl-enzyme intermediate of lysozyme
	Movie: Neuraminidase in complex with Tamiflu
Enzyme Chemistry part 2 (PDF, 8 MB)
	Movie: Triosephosphate isomerase
	Movie: Proteasome in complex with inhibitor bortezomib
	Movie: Tosyl-a-chymotrypsin
	Movie: Carboxypeptidase A in complex with inhibitor
	Movie: ACE in complex with inhibitor Lisinopril
	Movie: HIV-1 Protease complexed with inhibitor
	Movie: Aldolase in complex with dihydroxyacetone phosphate
	Movie: Substrate binding and catalysis mechanism of aldolase
	Movie: Ternary complex of ADH-NAD-DMSO
	Movie: Isosteric NAD analogues bound to ADH
	Movie: Ternary complex of cytochrome P450 - carbon monoxide - substrate
	Movie: Cytochrome P450 complexed with Hydroxycamphor(Catalytic product)
Biosynthesis of Natural Products - Terpenes (PDF, 2 MB)
	Movie: Oxidosqualene-Lanosterol-Cyclase
Biosynthesis of Natural Products - Polyketides (PDF, 5 MB)
	Movie: Mammalian Fatty Acid Synthase
Biosynthesis of Natural Products - Shikimic acid (PDF, 659 KB)
Biosynthesis of Natural Products - Alkaloids (PDF, 1 MB)